Endocrine Abstracts

Vitamin D (VD) now considered a steroid hormone, has been correlated with male reproductive disorders. The activity of VD is mediated through its receptor (VDR), distributed in various tissues including reproductive tissues. VDR polymorphism located in the promoter region of the gene, rs17883968 (Cdx2) G → A associated with transcriptional activity. The aim of this study was to assess both seminal and serum VD levels in a group of infertile patients (n=87, media...

Male infertility arises as a global public health in the context of the dramatic decrease in birth rates. However, the underlying causes of male infertility remain unknown in many cases. An increasing number of studies suggest that environmental and behavioral factors (smoking, drinking, etc) may affect the hormone levels and other pathways involved in male fertility. The aim of this study was to investigate the influence of various environmental factors and hormonal profiles ...

Male infertility arises as a global public health in the context of the dramatic decrease in birth rates, within a complex picture of hormonal, genetic and epigenetic factors. However, the underlying causes of male infertility remain unknown in many cases. Our study included samples (n = 82, median: 34 years, range 20–55 years) obtained from men investigating couple infertility and from a normal control group (n = 11, median: 29 years, range 21–55 y...